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Drugs used off label may have unrecognized safety and efficacy problems.
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The four lipotropics are methionine, choline, inositol, and betaine. How they work is this: Lipotropics increase production of lecithin in the liver, helping to keep cholesterol more soluble and lessening deposits in the blood vessels. They prevent accumulation of fats in the liver and they detoxify amines which are by-products of protein metabolism.
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Based on the results from the pivotal studies published this week, it appears that roflumilast provides added activity on top of other commonly used treatments for COPD,